Olga Penagarikano

Olga Penagarikano


Start Year: 
2016
Department: 
Pharmacology
Institution: 
University of Basque Country
Current Institution: 
University of Basque Country
Project Title: 

Neuropsychopharmacology of oxytocin in autism spectrum disorder.

Abstract: 

Autism Spectrum Disorder (ASD) comprise a group of neurodevelopmental disorders characterized by deficits in social and communication skills. Dysfunction in the oxytocin system has been associated with social deficits in autism and other neuropsychiatric disorders. The proposed project is based on past findings revealing oxytocin deficits in a well validated mouse model of ASD and improved social behavior after oxytocin administration in this model. I want to study how a deficit in the oxytocin system affects the release of two interacting neurotransmitters extensively linked to social behavior -dopamine and serotonin- in the nucleus accumbens, a structure associated to processing rewarding cues, including social reward. In addition, I want to probe the effect of oxytocin administration on these interacting neurotransmitter systems. This could help identify candidate targets for therapeutic intervention that may improve social deficits.

input:focus, select:focus, textarea:focus { border-color: #2d3e50; } a { color: #2d3e50; } .radio i, .checkbox i { color: #2d3e50; } .radio i:before { background-color: #2d3e50; } .button, .btn-default { border-color: #2d3e50; background-color: #2d3e50; } .button:hover { color: #2d3e50; } .page-header-top { background-color: #2d3e50; } .page-header-bottom-alt { background-color: #2d3e50; } .page-intro:after { background-color: #2d3e50; } .page-intro:before { background-color: #2d3e50; } .page-content-section-bg { background-color: #2d3e50; } .page-content-section-bg:before { background-color: #2d3e50; } .page-content-section-border { border-top-color: #2d3e50; } .page-footer { background-color: #2d3e50; } .block-head-1 { border-bottom-color: #2d3e50; } .block-head-1 i { background-color: #2d3e50; } .block-head-2:after { background-color: #2d3e50; } .block-head-2 i:after, .block-head-2 i:before { background-color: #2d3e50; } .block-head-3 { border-bottom-color: #2d3e50; } .block-head-3 i:after { background-color: #2d3e50; } .block-head-4:after { background-color: #2d3e50; } .block-head-7 { border-bottom-color: #2d3e50; } .block-head-7:after { background-color: #2d3e50; } .page-content-section-bg .block-head-3 i { color: #2d3e50; } .main-search button { color: #2d3e50; } .main-search button:after { background: #2d3e50; } .main-nav li a { color: #2d3e50; } .main-nav li a:before { background-color: #2d3e50; } .main-nav li ul { background-color: #2d3e50; } .main-nav li li:hover > a, .main-nav li li.active > a, #block-newsletter-newsletter-subscribe .form-submit:hover, .block-product-details .add-wishlist .button-alt:hover, .block-product-details-2 .add-wishlist .button-alt:hover { color: #2d3e50; } .main-nav .switcher { border-color: #2d3e50; background-color: #2d3e50; } .main-nav .mega > div { background-color: #2d3e50; } #block-newsletter-newsletter-subscribe .form-submit, .btn-primary:hover, .btn-primary:focus, .btn-primary:active { border-color: #2d3e50; background-color: #2d3e50; } .art-portfolio ol li.active, .ui-slider-horizontal .ui-slider-handle, .ui-slider-horizontal .ui-slider-range, .btn-primary.link { background-color: #2d3e50; } .btn-primary, .button:hover, .btn-default:hover, .btn-default:focus, .btn-default:active { border-color: #2d3e50; color: #2d3e50; } .btn-primary.link:hover, .btn-primary.link:focus, .btn-primary.link:active { color: #2d3e50; } } @media screen and (max-width: 767px) { /* phone */ .main-nav ul { background-color: #2d3e50; } .main-nav li a { color: #ecf0f1; } .main-nav li ul { background: #e9e9e9; } .main-nav li li { border-top-color: #2d3e50; } .main-nav li li a { color: #2d3e50; } .main-nav li li a:hover { background-color: #2d3e50; color: #fff; } .main-nav li li ul { border-top-color: #2d3e50; } .main-nav .mega ul li { border-top-color: #2d3e50; } } .slider-revolution .fa:after { background-color: #2d3e50; } .slider-revolution .title { border-top-color: 1px solid #2d3e50; border-bottom-color: 1px solid #2d3e50; } .slider-revolution .button-my { border-color: #2d3e50; background-color: #2d3e50; } .slider-revolution .button-my:hover { color: #2d3e50; } .pagination-1 a:hover { border-color: #2d3e50; color: #2d3e50; } .pagination-1 .active, .pagination-1 .active:hover { border-color: #2d3e50; background: #2d3e50; } .pagination-2 a:hover { color: #2d3e50; } .pagination-2 .active, .pagination-2 .active:hover { background: #2d3e50; } .pagination-3 a:before { box-shadow: inset 0 0 0 1px #2d3e50; } .pagination-3 .active:before, .pagination-3 .active:hover:before { background: #2d3e50; } .pagination-4 a:hover { border-color: #2d3e50; } .pagination-4 .active { border-color: #2d3e50; background: #2d3e50; } .pagination-5 a { border-color: #2d3e50; background-color: #2d3e50; color: #2d3e50; } .block-benefits div:hover { border-color: #2d3e50; background-color: #2d3e50; } .block-benefits i { color: #2d3e50; } .block-benefits-2 li i { color: #2d3e50; } .block-benefits-2 .tabs a:hover { border-color: #2d3e50; background-color: #2d3e50; } .block-benefits-2 .tabs .active a, .block-benefits-2 .tabs .active a:hover { color: #2d3e50; } .block-benefits-3 i { color: #2d3e50; } .block-about .button { border-color: #2d3e50; color: #2d3e50; } .block-about .button:hover { background: #2d3e50; color: #ecf0f1; } .block-about .owl-prev:hover, .block-about .owl-next:hover { color: #2d3e50; } .block-about-2 .bar { background: #2d3e50; } .block-about-2 .value { color: #2d3e50; } .block-about-4 .owl-pagination div { border-color: #2d3e50; background: #2d3e50; } .block-about-5 .owl-prev, .block-about-5 .owl-next { display: inline-block; border-color: #2d3e50; background-color: #2d3e50; } .block-about-5 .owl-prev:hover, .block-about-5 .owl-next:hover { color: #2d3e50; } .block-about-6 .icons a:hover { color: #2d3e50; } .block-mission .year { background: #2d3e50; } .block-mission .years a:after { border-bottom-color: #2d3e50; } .block-recent-works ol li:hover { color: #2d3e50; } .block-recent-works ol .active { border-color: #2d3e50; background: #2d3e50; } .block-recent-works .description { background: #2d3e50; } .block-recent-works .description:before { border-right-color: #2d3e50; } .block-recent-works-3 h3 { border-top-color: #2d3e50; } .block-recent-works-3 .link { border-color: #2d3e50; } .block-recent-works-3 .fancybox { background-color: #2d3e50; } .block-recent-works-3 .owl-pagination div { border-color: #2d3e50; background: #2d3e50; } .block-recent-works-4:before { background: #2d3e50; } .block-recent-works-4 .fancybox { background: #2d3e50; } .block-recent-works-4 .owl-prev:hover, .block-recent-works-4 .owl-next:hover { color: #2d3e50; } .block-recent-works-6 a:before { background: #2d3e50; } .block-recent-works-6 .owl-prev, .block-recent-works-6 .owl-next { border-color: #2d3e50; background: #2d3e50; } .block-recent-works-6 .owl-prev:hover, .block-recent-works-6 .owl-next:hover { color: #2d3e50; } .block-portfolio ol li:hover { color: #2d3e50; } .block-portfolio ol li.active { border-bottom-color: #2d3e50; } .block-portfolio ul .pic span:after, .block-portfolio ul .pic span:before { background: #2d3e50; } .block-portfolio ul .pic span i { color: #2d3e50; } .block-portfolio-2 ol li:hover { color: #2d3e50; } .block-portfolio-2 ol li.active { background: #2d3e50; } .block-portfolio-2 ul .pic:before { background: #2d3e50; } .block-portfolio-2 ul .pic a { background: #2d3e50; } .block-portfolio-2 ul .pic a:hover { color: #2d3e50; } .block-portfolio-3 ol li:hover { color: #2d3e50; } .block-portfolio-3 ol li.active { background: #2d3e50; } .block-portfolio-4 h3 { border-top-color: #2d3e50; } .block-portfolio-4 .link { border-color: #2d3e50; } .block-portfolio-4 .fancybox { background: #2d3e50; } .block-portfolio-5 ol li:hover { color: #2d3e50; } .block-portfolio-5 ol li.active { background: #2d3e50; } .block-portfolio-5 .info:before { background: #2d3e50; } .block-portfolio-6 ol li:hover { color: #2d3e50; } .block-portfolio-6 ol li.active { background: #2d3e50; } .block-portfolio-6 ul a:before { background: #2d3e50; } .block-portfolio-7 ol li:hover { color: #2d3e50; } .block-portfolio-7 ol li.active { background: #2d3e50; } .block-portfolio-7 ul li:before { background: #2d3e50; } .block-portfolio-7 ul a:hover { color: #2d3e50; } .block-portfolio-8 li div:before { background: #2d3e50; } .block-portfolio-8 li a { background: #2d3e50; } .block-clients .owl-prev, .block-clients .owl-next { color: #2d3e50; } .block-testimonials-3 .carousel h3 { border-bottom-color: #2d3e50; } .block-testimonials-3 .owl-pagination div { border-color: #2d3e50; } .block-testimonials-3 .owl-pagination .active { background: #2d3e50; } .block-testimonials-4 .owl-prev, .block-testimonials-4 .owl-next { border-color: #2d3e50; background: #2d3e50; } .block-testimonials-4 .owl-prev:hover, .block-testimonials-4 .owl-next:hover { color: #2d3e50; } .block-services li a { border-color: #2d3e50; } .block-services li a:hover { background-color: #2d3e50; } .block-services-2 li a:hover { background: none; } .block-services-2 li a:after { box-shadow: inset 0 0 0 2px #2d3e50; } .block-services-2 li a:hover:after { background-color: #2d3e50; } .block-services-3 li a:hover { background: none; } .block-services-3 li a:after { box-shadow: inset 0 0 0 2px #2d3e50; } .block-services-3 li a:before { background: #2d3e50; box-shadow: inset 0 0 0 2px #2d3e50; } .block-services-3 li a:hover:after { background-color: #2d3e50; } .block-services-4 li a { border-color: #2d3e50; } .block-services-4 li a:hover { background-color: #2d3e50; } .block-services-5 li i { color: #2d3e50; } .block-services-5 li i:hover { background: #2d3e50; } .block-services-6 h3 span { color: #2d3e50; } .block-services-6 li a { border-color: #2d3e50; background: #2d3e50; } .block-services-6 li a:hover { color: #2d3e50; } .block-services-7 .info i { background: #2d3e50; } .block-services-7 .carousel .active { background: #2d3e50; } .block-services-7 .carousel .owl-prev, .block-services-7 .carousel .owl-next { border-color: #2d3e50; background: #2d3e50; } .block-services-7 .carousel .owl-prev:hover, .block-services-7 .carousel .owl-next:hover { color: #2d3e50; } .block-pricing dt { color: #2d3e50; } .block-pricing .price:before { background: #2d3e50; } .block-pricing li:hover .inner { background: #2d3e50; } .block-pricing li:hover .button { color: #2d3e50; } .block-pricing li:hover .button:hover { background: #2d3e50; } .page-content-section .block-pricing .inner { box-shadow: 0 0 0 1px #2d3e50; } .block-pricing-2 dt { color: #2d3e50; } .block-pricing-2 .price { background: #2d3e50; } .block-pricing-2 .button { color: #2d3e50; } .block-pricing-2 li:hover .inner { background: #2d3e50; } .block-pricing-2 li:hover .button:hover { background: #2d3e50; } .block-progress li i { border-color: #2d3e50; color: #2d3e50; } .block-team-2 .pic:before { background-color: #2d3e50; } .block-team-2 .icons a { color: #2d3e50; } .block-team-3 .pic:before { background-color: #2d3e50; } .block-team-3 .icons a { color: #2d3e50; } .block-team-3 .info h3 { color: #2d3e50; } .block-team-list .pic span:after { background-color: #2d3e50; } .block-team-list .icons a:hover { color: #2d3e50; } .block-team-list .icons a:before { background: #2d3e50; } .block-team-list .skills { border-top-color: #2d3e50; border-bottom-color: #2d3e50; } .block-team-grid .pic:before { background-color: #2d3e50; } .block-skills i:before { background-color: #2d3e50; } .block-skills .bar { border-color: #2d3e50; background-color: #2d3e50; } .block-skills-2 i:before { background-color: #2d3e50; } .block-skills-2 .bar { border-color: #2d3e50; background-color: #2d3e50; } .block-capabilities h3 { color: #2d3e50; } .block-capabilities-2 h3 { color: #2d3e50; } .block-recent-posts .info { background-color: #2d3e50; } .block-recent-posts-2:before { background-color: #2d3e50; } .block-recent-posts-2 li .button { color: #2d3e50; } .block-recent-posts-2 li .button:hover { background-color: #2d3e50; } .block-recent-posts-2 .button-more { color: #2d3e50; } .block-recent-posts-2 .button-more:hover { background-color: #2d3e50; } .block-featured-posts .pic:before { background-color: #2d3e50; } .block-blog-list .link { background: #2d3e50; } .block-blog-list .date:before { background-color: #2d3e50; } .block-blog-list .date-alt { background-color: #2d3e50; } .block-blog-list .zoom { background-color: #2d3e50; } .block-blog-grid .link { background: #2d3e50; } .block-blog-grid .date:before { background-color: #2d3e50; } .block-blog-grid .pic:hover .date { color: #2d3e50; } .block-blog-grid .zoom { color: #2d3e50; } .block-blog-details .date:before, .block-blog-details .reply:before, .block-blog-details .type:before { background-color: #2d3e50; } .block-blog-details .date-alt { background-color: #2d3e50; } .block-blog-details .share a:before { border-color: #2d3e50; background: #2d3e50; } .block-blog-details .share a:hover { color: #2d3e50; } .block-blog-details .about:before { background: #2d3e50; } .block-catalog-toolbar .view a:hover { border-color: #2d3e50; color: #2d3e50; } .block-catalog-toolbar .view .active, .block-catalog-toolbar .view .active:hover { border-color: #2d3e50; background: #2d3e50; } .block-catalog-toolbar .direction { border-color: #2d3e50; background: #2d3e50; } .block-catalog-toolbar .direction:hover { color: #2d3e50; } .block-catalog-grid .pic:before { background: #2d3e50; } .block-catalog-grid .badge { background: #2d3e50; } .block-catalog-grid .price { color: #2d3e50; } .block-catalog-grid .owl-prev, .block-catalog-grid .owl-next { border-color: #2d3e50; background: #2d3e50; } .block-catalog-grid .owl-prev:hover, .block-catalog-grid .owl-next:hover { color: #2d3e50;; } .block-catalog-list .pic:after { background-color: #2d3e50; } .block-catalog-list .badge:before { background-color: #2d3e50; } .block-catalog-list .price { color: #2d3e50; } .block-catalog-list .owl-prev, .block-catalog-list .owl-next { border-color: #2d3e50; background-color: #2d3e50; } .block-catalog-list .owl-prev:hover, .block-catalog-list .owl-next:hover { color: #2d3e50;; } .block-product-details .price { color: #2d3e50; } .block-product-details .button-alt { color: #2d3e50; } .block-product-details-2 .button-alt { color: #2d3e50; } .block-product-details-2 .share a:before { background-color: #2d3e50; box-shadow: 0 0 0 2px #2d3e50; } .block-product-details-2 .share a:hover { color: #2d3e50; } .block-product-info .owl-prev, .block-product-info .owl-next { border-color: #2d3e50; background-color: #2d3e50; } .block-product-info .owl-prev:hover, .block-product-info .owl-next:hover { color: #2d3e50; } .block-product-tabs .head .active { color: #2d3e50; } .block-product-tabs .head .active:before { border-top-color: #2d3e50; } .block-shopping-cart th { border-top-color: #2d3e50; color: #2d3e50; } .block-shopping-cart .price { color: #2d3e50; } .block-shopping-cart .remove { border-color: #2d3e50; background-color: #2d3e50; } .block-shopping-cart .remove:hover { color: #2d3e50; } .block-shopping-cart .quantity a { color: #2d3e50; } .block-shopping-cart .empty td { border-bottom-color: #2d3e50; } .block-shopping-cart-totals dd { color: #2d3e50; } .block-shopping-cart-totals .button-alt { color: #2d3e50; } .block-checkout-order td:last-child { color: #2d3e50; } .block-checkout-payment label { color: #2d3e50; } .block-welcome .icons i:after { border-color: #2d3e50; background: #2d3e50; } .block-welcome .icons a:hover i { color: #2d3e50; } .block-pasteboard:before { background: #2d3e50; } .block-pasteboard .icons a:hover { color: #2d3e50; } .block-map-3 .block-head { color: #2d3e50; } .block-contacts ul li:after, .block-contacts ul li:before { border-color: #2d3e50; background-color: #2d3e50; } .block-contacts ul li:before { background-color: #fff; } .block-contacts ul li span { border-bottom-color: #2d3e50; } .block-contacts ul .active { color: #2d3e50; } .block-contacts ul .active:before { background-color: #2d3e50; } .block-contacts ol { border-top-color: #2d3e50; } .block-contacts ol li { color: #2d3e50; } .block-contacts ol li i:after { background-color: #2d3e50; } .block-feedback .message i, .block-feedback-2 .message i { color: #2d3e50; } .block-not-found h3 { color: #2d3e50; } .block-not-found .pic:before { background-color: #2d3e50; } .block-not-found .pic div:before { background-color: #2d3e50; } .block-not-found-2 .button { color: #2d3e50; } .block-not-found-2 .button:hover { background: #2d3e50; } .block-coming-soon li:before { background-color: #2d3e50; } .block-coming-soon-2 li:after { background-color: #2d3e50; } .widget-categories a:hover, .widget-categories a.active { color: #2d3e50; } .widget-top-posts a:hover { color: #2d3e50; } .widget-text hr { border-top-color: #2d3e50; } .widget-text em { color: #2d3e50; } .widget-archive a:hover, .widget-archive a.active { color: #2d3e50; } .widget-tags a:hover { color: #2d3e50; } .widget-categories-filter a:hover { color: #2d3e50; } .widget-categories-filter .active { color: #2d3e50; } .widget-categories-filter .active span { background-color: #2d3e50; } .widget-price-filter .ui-slider-range { background-color: #2d3e50; } .widget-price-filter .ui-slider-handle { background-color: #2d3e50; } .widget-color-filter .active:before { border-color: #2d3e50; } .widget-top-products .pic i { background-color: #2d3e50; } .main-nav ul { background-color: #2d3e50; }